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    2018-7-23 · UCLA lab tests showed that lutein reduced prostate cancer cell growth by 25% while lycopene reduced cell growth by 20%. When lutein and lycopene were combined, prostate cancer cell growth was reduced by 32%, thus indicating that both nutrients together help protect against prostate cancer better than either nutrient alone.

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  • Prostate and breast cancer in four Nordic countries: A ...

    2017-8-10 · Prostate cancer mortality trends, all ages combined. After a period of gradually increasing prostate cancer mortality rates during the 1980s and early 1990s, significant annual declines of 1.9–2.7% were observed from the mid‐ to late‐1990s in all countries except Denmark, where rates stabilized from about 2000 (Fig. 1; Table 1).

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    2018-4-18 · Copenhagen, Denmark (UroToday.com) At GU ASCO 2018, Dr. Maha Hussain presented the data from the PROSPER study, which was an incredibly important study looking at the role for enzalutamide (ENZA) in the setting of non-metastatic castration-resistant prostate …

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    2021-6-11 · Copenhagen, Denmark (UroToday.com) At GU ASCO 2018, Dr. Maha Hussain presented the data from the PROSPER study, which was an incredibly important study looking at the role for enzalutamide (ENZA) in the setting of non-metastatic castration-resistant prostate cancer (nmCRPC).There was a 71% risk reduction of metastases; MFS was 36.6 months in the ENZA arm …

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    2015-8-17 · For prostate cancer, there was a significant interaction between country and having an OS co-twin (P = 0.04). A higher risk was suggested for OS than for SS males in Denmark (IRR, 1.14; 95% CI, 0.96–1.34), whereas the opposite was indicated in Sweden (IRR, 0.93; 95% CI, 0.83–1.03; results not shown).

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    2013-11-14 · Two Studies Demonstrate Efficacy for Prostate Cancer Treated With CyberKnife System November 14, 2013 — Accuray Inc. announced the publication of two papers stemming from a large multi-center study of CyberKnife stereotactic body radiotherapy (SBRT) led by investigators at the University of California, Los Angeles (UCLA).

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    2020-11-12 · Large study confirms value of CT lung cancer screening. By Brian Casey, AuntMinnie.com staff writer. November 12, 2020 — CT lung cancer screening reduces the risk of death from lung cancer, according to a new meta-analysis that combines data from all randomized controlled trials performed so far. In fact, CT lung screening compares favorably to breast …

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  • Overall survival of patients with metastatic prostate ...

    2019-11-21 · 198. Background: Morbidity and mortality amongst patients diagnosed with metastatic prostate cancer remains high and androgen deprivation therapy is the mainstay of hormonal treatments for these patients. The gonadotropin-releasing hormone (GnRH) antagonist, degarelix, has a fast and profound onset of action and compares favorably with GnRH agonists in terms of …

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  • Genomic aberration based molecular signatures efficiently ...

    mutations are also present in prostate adenocarcinoma, in up to 5-10% of metastatic prostate cancer cases [3], it was recently shown that PARP inhibitors were also effective in such prostate cancer cases [4]. HRD can be induced by germline or somatic BRCA1/2 genetic mutations; however, it can also be present in tumors with intact BRCA1/BRCA2 genes.

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    AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics-- Oct 22-26, 2007; San Francisco, CA C238 Thapsigargin (TG) is a highly lipophilic, cytotoxic natural product isolated in high yield from the umbelliferous plant Thapsia garganica. In the NCI 60 Cancer Cell Line Screen, TG has an GI50 of ~10-10 Molar which compares favorably with chemotherapeutic …

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    2021-8-19 · Grzegorz Lukasz Fojecki1, Jacob Johan Friis1, Stefan Tiessen1, Steen Carlsson2, Lars Lund1 1Odense University Hospital, Odense, Denmark 2Zealand University Hospital, Roskilde, Denmark O2-04 - Preclinical study evaluating intraprostatic ethanol injection via microporous needle as a potential treatment of organ confined prostate cancer.

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  • A comparative study of PCS and PAM50 prostate cancer ...

    2021-2-2 · Two prostate cancer (PC) classification methods based on transcriptome profiles, a de novo method referred to as the 'Prostate Cancer Classification System' (PCS) and a variation of the ...

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    Introduction. Bones are one of the most common sites of metastases for many types of solid cancers (1-4).Bone metastases have an increased risk of serious skeletal-related events (SREs), such as pathological fractures, pain, hypercalcemia, and spinal cord compressions, which can seriously impair patients' quality of life (5-9).Bone metastases also lead to a significant increase in mortality ...

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    2017-8-25 · Wow! And Ugh! That is a far higher percentage that were dying of prostate cancer in the US during the same period. Back in the 1970s, about a third of men diagnosed in the US were dying of prostate cancer within 5 years, but survival had improved to the upper 90%s by 1998 when the Danish study started and reached nearly 100% by 2011 when it ended.

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    2020-11-12 · Large study confirms value of CT lung cancer screening. By Brian Casey, AuntMinnie.com staff writer. November 12, 2020 — CT lung cancer screening reduces the risk of death from lung cancer, according to a new meta-analysis that combines data from all randomized controlled trials performed so far. In fact, CT lung screening compares favorably to breast screening, according to a paper in the ...

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  • Long-term Efficacy and Safety of Enzalutamide Monotherapy ...

    2015-11-1 · Long-term enzalutamide monotherapy for up to 2 yr in men with noncastrate hormone-naïve prostate cancer is associated with large, sustained reductions in prostate-specific antigen, signals indicating a favorable tumor response, and favorable tolerability, with minimal negative effects on total body bone mineral density.

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  • ASCO: Enzalutamide Monotherapy in Prostate Cancer Achieves ...

    2013-6-5 · CHICAGO-Monotherapy with enzalutamide (Xtandi) achieved a 'high PSA response rate and marked PSA decline' in patients with hormone-naïve prostate cancer after 6 months in a single-arm, multicenter phase II study, reported Matthew Raymond Smith, MD, PhD, of the Massachusetts General Hospital Cancer Center, Boston (abstract 5001).Efficacy was similar to …

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    2021-1-23 · Niacin deficiency promotes cancer by decreasing genomic stability, increasing the chances both for mutation and survival of mutated cancer cells. Studies indicate that niacin deficiency delays DNA repair, promotes accumulation of DNA strand breaks, chromosomal translocations, telomere erosion typical of aging, and promotes cancer.

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  • More on statins and the management of prostate cancer ...

    2017-8-25 · Wow! And Ugh! That is a far higher percentage that were dying of prostate cancer in the US during the same period. Back in the 1970s, about a third of men diagnosed in the US were dying of prostate cancer within 5 years, but survival had improved to the upper 90%s by 1998 when the Danish study started and reached nearly 100% by 2011 when it ended.

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    2004-9-1 · Access and take the CME test online and receive 1 hour of AMA PRA category 1 credit at CME.TheOncologist.com. Purpose.To compare the efficacy, in regard to time to progression (TTP) and objective response rate (ORR), of letrozole (Femara ®; Novartis Pharma AG; Basel Switzerland), an oral aromatase inhibitor, with that of tamoxifen (Tamofen ®; Leiras OY; Turku, Finland) as first …

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  • ASCO: Enzalutamide Monotherapy in Prostate Cancer

    2013-6-5 · CHICAGO-Monotherapy with enzalutamide (Xtandi) achieved a 'high PSA response rate and marked PSA decline' in patients with hormone-naïve prostate cancer after 6 months in a single-arm, multicenter phase II study, reported Matthew Raymond Smith, MD, PhD, of the Massachusetts General Hospital Cancer Center, Boston (abstract 5001).Efficacy was similar to castration, but in contrast with ...

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    2018-8-2 · Prostate cancer (PCa) is a disease of mutated and misregulated genes. However, primary prostate tumors have relatively few mutations, and only three genes (ERG, PTEN, and SPOP) are recurrently mutated in more than 10% of primary tumors.On the other hand, metastatic castration-resistant tumors have more mutations, but, with the exception of the androgen receptor gene (AR), no …

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    2021-2-18 · Study Training Dogs To Detect Prostate Cancer Gets One Paw Closer To A 'Robotic Nose' To Diagnose The Disease, Including Most Lethal Form A study by Medical Detection Dogs, the Prostate …

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    2014-2-12 · JACKSONVILLE, Fla., Feb. 11, 2014 /PRNewswire -- Five years after having proton therapy for early- and intermediate-risk prostate cancer, 99 percent of men are living cancer-free and with ...

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    2021-5-14 · Purpose: A possible association between metformin use and the development of prostate cancer (PCa) has been reported. However, there is limited information on the impact of long-term metformin use on serum prostate-specific antigen (PSA) levels. We investigated the association between exposure to metformin and PSA levels among diabetic patients who were not previously diagnosed …

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    2018-7-23 · UCLA lab tests showed that lutein reduced prostate cancer cell growth by 25% while lycopene reduced cell growth by 20%. When lutein and lycopene were combined, prostate cancer cell growth was reduced by 32%, thus indicating that both nutrients together help protect against prostate cancer better than either nutrient alone.

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    2016-2-27 · Cancer cells behave differently from healthy cells in many ways. Healthy cells rely on structures called mitochondria to provide them with energy via a process that requires oxygen. However cancer cells don't rely on this process, and instead release energy by breaking down sugars outside of the mitochondria. This may explain why cancer cells are able to thrive even …

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    Early Diagnosis of Prostate Cancer Through PSA Testing Saves Lives. Dr. Catalona was invited to give the Ramon Guiteras Lecture at the recent annual meeting of the American Urological Association. This lecture, one of the most prestigious at the conference, is presented in honor of the surgeon who founded the American Urological Association.

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    Large prostate size significantly correlated with increased time to PSA failure (p = 0.013) and it was independent of the significant effects of Gleason score, PSA, disease stage (p <0.001 ...

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    2018-7-29 · Prostate cancer is the major cause of cancer death in men living in developed countries. Large autopsy studies found that patients that presented prostate cancer demonstrated metastatic disease in 35% of cases. Prostate cancer metastases were 90% bone metastases, with 90% of the bone metastases involved

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  • Overall survival of patients with metastatic prostate ...

    2018-2-26 · 198. Background: Morbidity and mortality amongst patients diagnosed with metastatic prostate cancer remains high and androgen deprivation therapy is the mainstay of hormonal treatments for these patients. The gonadotropin-releasing hormone (GnRH) antagonist, degarelix, has a fast and profound onset of action and compares favorably with GnRH agonists in terms of progression-free …

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    2013-4-23 · Results: A PSA‐based screening program reduced the relative risk of prostate cancer mortality by 44% over 14 years. Overall, 293 men needed to be invited for screening and 12 to be diagnosed to prevent one prostate cancer death. Attending a screening program for prostate

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  • Prostate and breast cancer in four Nordic countries: A ...

    2017-8-10 · Prostate cancer mortality trends, all ages combined. After a period of gradually increasing prostate cancer mortality rates during the 1980s and early 1990s, significant annual declines of 1.9–2.7% were observed from the mid‐ to late‐1990s in all countries except Denmark, where rates stabilized from about 2000 (Fig. 1; Table 1).

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  • EAU18 - Copenhagen. PROSPER Trial. - Advanced Prostate...

    2018-4-18 · Copenhagen, Denmark (UroToday.com) At GU ASCO 2018, Dr. Maha Hussain presented the data from the PROSPER study, which was an incredibly important study looking at the role for enzalutamide (ENZA) in the setting of non-metastatic castration-resistant prostate cancer (nmCRPC).

    Get Price
  • EAU 2018: Patient-Reported Outcome Measures in Men

    2021-6-11 · Copenhagen, Denmark (UroToday.com) At GU ASCO 2018, Dr. Maha Hussain presented the data from the PROSPER study, which was an incredibly important study looking at the role for enzalutamide (ENZA) in the setting of non-metastatic castration-resistant prostate cancer (nmCRPC).There was a 71% risk reduction of metastases; MFS was 36.6 months in the ENZA arm …

    Get Price
  • Risk of Sex-Specific Cancers in Opposite-Sex and Same

    2015-8-17 · For prostate cancer, there was a significant interaction between country and having an OS co-twin (P = 0.04). A higher risk was suggested for OS than for SS males in Denmark (IRR, 1.14; 95% CI, 0.96–1.34), whereas the opposite was indicated in Sweden …

    Get Price
  • Two Studies Demonstrate Efficacy for Prostate Cancer ...

    2013-11-14 · Two Studies Demonstrate Efficacy for Prostate Cancer Treated With CyberKnife System November 14, 2013 — Accuray Inc. announced the publication of two papers stemming from a large multi-center study of CyberKnife stereotactic body radiotherapy (SBRT) led by investigators at the University of California, Los Angeles (UCLA).

    Get Price
  • Large study confirms value of CT lung cancer screening ...

    2020-11-12 · Large study confirms value of CT lung cancer screening. By Brian Casey, AuntMinnie.com staff writer. November 12, 2020 — CT lung cancer screening reduces the risk of death from lung cancer, according to a new meta-analysis that combines data from all randomized controlled trials performed so far. In fact, CT lung screening compares favorably to breast screening, according to a paper in the ...

    Get Price
  • Overall survival of patients with metastatic prostate ...

    2019-11-21 · 198. Background: Morbidity and mortality amongst patients diagnosed with metastatic prostate cancer remains high and androgen deprivation therapy is the mainstay of hormonal treatments for these patients. The gonadotropin-releasing hormone (GnRH) antagonist, degarelix, has a fast and profound onset of action and compares favorably with GnRH agonists in terms of progression-free …

    Get Price
  • Genomic aberration based molecular signatures

    mutations are also present in prostate adenocarcinoma, in up to 5-10% of metastatic prostate cancer cases [3], it was recently shown that PARP inhibitors were also effective in such prostate cancer cases [4]. HRD can be induced by germline or somatic BRCA1/2 genetic mutations; however, it can also be present in tumors with intact BRCA1/BRCA2 genes.

    Get Price
  • A novel thapsigargin prodrug demonstrates antitumor ...

    AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics-- Oct 22-26, 2007; San Francisco, CA C238 Thapsigargin (TG) is a highly lipophilic, cytotoxic natural product isolated in high yield from the umbelliferous plant Thapsia garganica. In the NCI 60 Cancer Cell Line Screen, TG has an GI50 of ~10-10 Molar which compares favorably with chemotherapeutic agents such as ...

    Get Price
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    An large, completely virtual study is ongoing for Loop users and the data will support Tidepool's submission of Loop to the FDA. To differentiate Tidepool Loop from the DIY-version, Tidepool Loop will have different colors, guardrails around certain settings, and a built-in tutorial for new users. ... Canada, Denmark, and The Netherlands ...

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